Salvage Radiosurgery for Selected Patients with Recurrent Malignant Gliomas
Table 4
Prognostic factors.
Variables
Bivariate analyses
Multivariate analyses
HR (95% CI)
value
HR (95% CI)
value
Age
1.04 (1.01–1.05)
Not significant
KPS (≤80 versus >80)
2.59 (1.55–4.3)
2.08 (0.28–0.83)
RPA
IV versus III
2.39 (1.18–4.82)
3.46 (1.61–7.46)
V versus III
6.32 (2.82–14.14)
7.29 (3.23–16.34)
Histology (GBM versus AA)
2.45 (1.53–3.94)
3.13 (1.79–5.48)
Tumour volume
1.04 (1.01–1.07)
Not significant
Treatment volume
1.03 (1.01–1.06)
*
Margin to PTV
0 versus ≥1
0.77 (0.67–0.87)
3.19 (1.91–5.31)
This variable was not considered for the multivariate analyses because of the strong correlation (0.97 Spearman’ s correlation coefficient) with tumour volume.
