BioMed Research International / 2014 / Article / Tab 4

Clinical Study

Salvage Radiosurgery for Selected Patients with Recurrent Malignant Gliomas

Table 4

Prognostic factors.

VariablesBivariate analysesMultivariate analyses
HR (95% CI) valueHR (95% CI) value

Age1.04 (1.01–1.05) Not significant
KPS (≤80 versus >80)2.59 (1.55–4.3) 2.08 (0.28–0.83)
RPA
 IV versus III2.39 (1.18–4.82) 3.46 (1.61–7.46)
 V versus III6.32 (2.82–14.14) 7.29 (3.23–16.34)
Histology (GBM versus AA)2.45 (1.53–3.94) 3.13 (1.79–5.48)
Tumour volume   1.04 (1.01–1.07)      Not significant
Treatment volume1.03 (1.01–1.06) *
Margin to PTV
 0 versus ≥10.77 (0.67–0.87) 3.19 (1.91–5.31)

This variable was not considered for the multivariate analyses because of the strong correlation (0.97 Spearman’ s correlation coefficient) with tumour volume.

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