Immunogenicity Studies of Bivalent Inactivated Virions of EV71/CVA16 Formulated with Submicron Emulsion Systems
Figure 3
EV71-specific VN antibody responses in mice vaccinated with single dose of inactivated EV71 virus formulated with different adjuvant. BALB/c mice () were vaccinated i.m. once with the candidate vaccine formulations: (-x-) no adjuvant, (-o-) PELC, and (-∆-) PELC/CpG. Blood samples were collected from vaccinated mice at different weeks and the antibody titers were determined by VN assays. Data are presented as mean titers with standard errors of six mice per group; the dotted horizontal line represents a VN titer of 40.
