Immunogenicity Studies of Bivalent Inactivated Virions of EV71/CVA16 Formulated with Submicron Emulsion Systems

Table 1

The composition and particle size of the designed emulsion-based adjuvants.

Emulsion adjuvant	Components^a	Particle size^b; (Mean ± STD, nm)
PELC	Squalene, PEG-b-PLACL, Span 85	338 ± 129
PELC(T)	Squalene, Tween 80, Span 85	284 ± 17
PELC(A)	Squalene, Tween 80, 𝛼-tocopherol	407 ± 155

aEmulsification process was performed using homogenizer under 6,000 rpm for 5 min.
^bData were represented as the mean with standard deviation (STD) of three samples.