Plastic Changes in the Spinal Cord in Motor Neuron Disease

Figure 1

Effects of lithium on survival and motor performance in G93A mice. The graphs report data from G93A mice with either saline or lithium. Lithium prolongs mice survival as shown by Kaplan-Meier survival curve. Lithium counteracts motor deterioration measured by stride length, paw grip endurance (PaGE), and rotarod. Values are given as the mean ± SEM. *𝑃≤0.05 compared with mice administered saline.

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