Antidiabetic Effect of Sida cordata in Alloxan Induced Diabetic Rats

Table 2

Antihyperglycemic activity of SCEE in glucose loaded alloxan induced diabetic animals.

Treatment	Dose (mg/kg)	Blood glucose concentration (mg/dL)
		0 min	60 min	120 min	180 min
SCEE	150	252.0 ± 4.4	315.0 ± 5.0*	321.7 ± 12.8*	266.0 ± 5.2*
	300	247.5 ± 5.0	292.0 ± 7.0*	303.3 ± 5.7*	236.7 ± 12.5*
Nondiabetic	—	84.5 ± 4.5	140.0 ± 6.4	112.0 ± 3.6	92.0 ± 4.8
Diabetic control	—	240.0 ± 4.5	379.7 ± 9.5	410.0 ± 5.0	342.0 ± 19.6
Glibenclamide	5	233.0 ± 5.7	270.0 ± 6.2*	295.0 ± 5.0*	228.7 ± 3.2*

Values expressed as means ± SD. *Significance difference (𝑃 < 0.05) against diabetic control. SCEE: S. cordata ethyl acetate fraction.