Research Article

Feleucins: Novel Bombinin Precursor-Encoded Nonapeptide Amides from the Skin Secretion of Bombina variegata

Table 2

Summary of the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of the three novel AMPs (bombinin, feleucin-BV1, and feleucin-BV2) described in this study. NA: not active. Haemolysis values are those effecting 100% lysis of red blood cells in 120 min.

PeptidesMIC (mg/L)MBC (mg/L) Haemolysis (mg/L)
S.  aureus E.  coli C.  albicans S.  aureus E.  coli C.  albicans Horse red cells

Bombinin8323232323264
Feleucin-BV1256NANA256NANA>512
Feleucin-BV2128NANA256NANA>512