Drug Release Kinetics and Front Movement in Matrix Tablets Containing Diltiazem or Metoprolol/λ-Carrageenan Complexes
Figure 1
Fraction of diltiazem released as a function of time in different dissolution media from matrices consisting of DTZ-CRG complex in water (empty circle), DTZ-GRG physical mixture in water (square), DTZ-HPMC physical mixture in water (diamond), DTZ-CRG complex in pH 1.2 (solid circle), and DTZ-CRG complex in pH 6.8 (solid triangle). The bars represent the standard deviation . Lines are simple interpolation of the experimental points.
