Collagen-Glycosaminoglycan Matrix Implantation Promotes Angiogenesis following Surgical Brain Trauma
Sustained increase of tissue concentrations of angiogenesis growth factors fibroblast growth factor- (FGF-2), platelet-derived growth factor (PDGF), and vascular endothelial growth factor (VEGF) in the lesion boundary zone (LBZ) of brains from of L+CG group compared to those from the Sham or L groups. (a) FGF2, (b) PDGF, and (c) VEGF protein concentrations as measured by an ELISA in brains of the Sham, L, and L+CG groups of rats. Data are the mean ± SD. , and , L and L+CG groups versus Sham group; +, ++ and +++, L versus L+CG.
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