DNA Methylation Pattern in Overweight Women under an Energy-Restricted Diet Supplemented with Fish Oil
Table 2
Anthropometric and serum variables from control and fish oil supplemented women before and after the 8-week weight loss treatment.
Control
Fish oil
Interaction
Weight loss treatment
Oral suppl.
Baseline
Endpoint
Baseline
Endpoint
Anthropometric
Age, years
35.1 ± 5.5
—
32.4 ± 5.0
—
Height, m
1.65 ± 0.06
—
1.61 ± 0.05
—
Weight, kg
82.9 ± 2.3
78.7 ± 3.0
78.8 ± 5.2
73.6 ± 5.6
ns.
ns.
BMI, kg/m2
30.7 ± 2.0
29.1 ± 2.6
30.5 ± 1.7
28.4 ± 1.8
ns.
ns.
SBP, mmHg
120.6 ± 9.6
121.8 ± 8.3
115.4 ± 9.5
113.1 ± 5.7
ns.
ns.
ns.
DBP, mmHg
67.2 ± 4.1
68.4 ± 2.9
72.1 ± 6.5
68.9 ± 5.6
ns.
ns.
ns.
Serum
Glucose, mg/dL
86.9 ± 4.6
85.1 ± 3.2
88.1 ± 6.0
90.6 ± 9.7
ns.
ns.
ns.
Insulin, mU/L
8.4 ± 4.0
8.2 ± 4.0
12.4 ± 6.7
8.3 ± 3.3
ns.
ns.
ns.
HOMA index
1.8 ± 0.9
1.7 ± 0.7
2.7 ± 1.5
1.8 ± 0.7
ns.
ns.
ns.
Leptin, g/mL
37.6 ± 10.7
25.4 ± 8.4
30.6 ± 14.5
18.5 ± 8.0
ns.
ns.
Total cholesterol, mg/dL
214.9 ± 49.0
200.1 ± 44.9
197.4 ± 46.5
185.4 ± 35.1
ns.
ns.
ns.
LDL cholesterol, mg/dL
132.5 ± 30.9
124.8 ± 26.9
114.0 ± 40.6
114.5 ± 29.7
ns.
ns.
ns.
HDL cholesterol, mg/dL
65.2 ± 21.2
58.2 ± 24.7
57.0 ± 11.0
52.7 ± 8.8
ns.
ns.
ns.
Triglycerides, mg/dL
85.9 ± 48.7
85.8 ± 26.1
131.9 ± 75.0
88.1 ± 35.3
ns.
ns.
ns.
Data represent mean ± SD (control ; fish oil group ). Differences within and between subjects were determined by a general linear model with repeated measures. ns.: not significant; SBP: systolic blood pressure; DBP: diastolic blood pressure; HOMA: homeostasis model assessment; Oral suppl.: effect of the oral supplementation of fish oil.
