BioMed Research International / 2014 / Article / Tab 2

Research Article

Multiple Regression Analysis of mRNA-miRNA Associations in Colorectal Cancer Pathway

Table 2

Candidate genes frequently involved in CRC pathways (modified from [4]).

Gene nameMolecular functionCRC pathway

APCTumor suppressor geneMSI and CIN
DCCTumor suppressor geneMSI and CIN
KRASOncogeneMSI and CIN
MLH1DNA mismatch repairMSI
MSH2DNA mismatch repairMSI
MSH6DNA mismatch repairMSI
SMAD2Tumor suppressorMSI and CIN
SMAD4Tumor suppressorMSI and CIN
TGFBR2Cell signalingMSI and CIN
TP53Tumor suppressorMSI and CIN