Umbilical Cord Blood-Derived Stem Cells Improve Heat Tolerance and Hypothalamic Damage in Heat Stressed Mice

Table 1

Effects of heat exposure on neuronal damage score of the brain (or the hypothalamus) in different groups of mice.

Treatment groups	Neuronal damage score (0–3)
(1) Non-WBH mice	0 (0, 0)
(2) Non-WBH mice treated with CD34^+ cells (1×10^5 cells/0.3 mL, i.v.)	0 (0, 0)
(3) Heated mice treated with vehicle saline (0.3 mL, i.v.)	2 (2, 2)^a
(4) Heated mice treated with CD34^+ cells (1×10^5 cells/0.3 mL, i.v.)	0.75 (0, 0.75)^b

Samples were measured 4 hours after whole body heating (WBH; 41.2°C for 1 houer) or the equivalent time period for non-heated group. ^acompared with non-WBH group (𝑃<0.01); ^bcompared with group 2 (𝑃<0.05). Data are means ± S.E.M. of 12 mice per group.