Conformational B-Cell Epitopes Prediction from Sequences Using Cost-Sensitive Ensemble Classifiers and Spatial Clustering

Table 2

Confusion matrix.

	Actually positive	Actually negative
Predict positive	Cost(+, +)	Cost(+, −)
Predict negative	Cost(−, +)	Cost(−, −)

Cost values are set according to different classification results. Generally, for a rare positive and prevalent negative samples, Cost(+, −) > Cost(−, +). And Cost(+, +) = Cost(−, −) = 0 denotes no penalty for a correctly predicted sample.