Research Article
Conformational B-Cell Epitopes Prediction from Sequences Using Cost-Sensitive Ensemble Classifiers and Spatial Clustering
Table 6
Performance of different machine learning methods, evaluated by LOOCV.
| Method | Bound dataset | Unbound dataset | | ACC | SN | SP | AUC | | ACC | SN | SP | AUC |
| ANN | 0.294 | 0.723 | 0.629 | 0.732 | 0.643 | 0.276 | 0.678 | 0.659 | 0.679 | 0.645 | KNN | 0.323 | 0.744 | 0.666 | 0.752 | 0.654 | 0.298 | 0.692 | 0.662 | 0.665 | 0.648 | SVM | 0.330 | 0.750 | 0.648 | 0.760 | 0.661 | 0.312 | 0.689 | 0.704 | 0.687 | 0.652 |
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