Alternative Splicing Generates Different Parkin Protein Isoforms: Evidences in Human, Rat, and Mouse Brain

Table 4

Parkin isoforms recognized by antibodies used in some studies.

Name	Target	Recognized Parkin isoforms
M73 (Shimura et al., 1999) [22]	124–137	H1, H4, H5, H8, H9, H10, H13, H14, H17, H20, H21
M74 (Shimura et al., 1999) [22]	293–306	H1, H2, H3, H4, H5, H6, H8, H10, H11, H14, H17, H20, H21
ParkA (Huynh et al., 2000) [23]	96–109	H1, H2, H3, H4, H5, H6, H8, H9, H10, H11, H13, H14, H17, H20, H21
ParkB (Huynh et al., 2000) [23]	440–415	H1, H2, H5, H6, H7, H8, H10, H11, H12, H14, H17, H18, H20, H21
HP6A (Schlossmacher et al., 2002) [24]	6–15	H1, H4, H5, H6, H9, H10, H13, H14, H16, H20
HP7A (Schlossmacher et al., 2002) [24]	51–62	H1, H4, H5, H6, H9, H10, H13, H14, H15, H20
HP1A (Schlossmacher et al., 2002) [24]	84–98	H1, H2, H3, H4, H5, H6, H8, H9, H10, H11, H13, H14, H17, H20, H21
HP2A (Schlossmacher et al., 2002) [24]	342–353	H1, H2, H3, H4, H5, H6, H7, H8, H11, H12, H17, H18, H20, H21
HP5A (Schlossmacher et al., 2002) [24]	453–465	H1, H2, H5, H6, H7, H8, H10, H11, H12, H14, H17, H18, H20, H21