Diazepam Potentiates the Antidiabetic, Antistress and Anxiolytic Activities of Metformin in Type-2 Diabetes Mellitus with Cooccurring Stress in Experimental Animals

Figure 2

The effect of MET, DZ, and their combination on DMS-induced alterations in percentage of open arm entries to total arm entries (a), percentage of open arm time spent to total arm time spent (b), and total arm entries (c) in EPM. All values are mean ± SEM (𝑛=6). ^a𝑃<0.05 compared to control, ^b𝑃<0.05 compared to DMS, ^c𝑃<0.05 compared to DMS+MET, and ^d𝑃<0.05 compared to DMS+DZ (repeated measure two-way ANOVA followed by Bonferroni test).

(a)

(b)

(c)