Comparison of Proton Pump Inhibitor and Histamine-2 Receptor Antagonist in the Prevention of Recurrent Peptic Ulcers/Erosions in Long-Term Low-Dose Aspirin Users: A Retrospective Cohort Study

Table 4

Univariate analysis of risk factors for recurrent ulcers/erosions in long-term low-dose aspirin users.

Variables	Relative risk	95% confidence interval	value
Age ≥ 60 years	0.4	0.1–1.6	0.2
Primary prevention	1.1	0.4–3.3	0.8
Male gender	2.5	0.5–11.6	0.3
Omeprazole group	0.2	0.08–0.7	0.008
Smoking	2.8	0.8–9.5	0.1
Alcohol consumption	3.0	0.5–19.3	0.2
Coffee consumption	0.4	0.05–3.2	0.4
Tea consumption	1.3	0.4–4.1	0.6
History of UGIB*	0.6	0.2–2.3	0.5
History of H. infection	0.9	0.3–2.6	0.9
Concomitant medication
Steroids	1.1	0.1–10.0	1.0
Use of NSAID^† <1 week	1.5	0.4–6.0	0.6

*UGIB: upper gastrointestinal bleeding.
^†NSAID: nonsteroidal anti-inflammatory drug.