Amelioration of Paracetamol-Induced Hepatotoxicity in Rat by the Administration of Methanol Extract of Muntingia calabura L. Leaves

Table 1

Effect of MEMC on percentage change of body and liver weight in PCM-induced hepatic injury rats.

Treatment	Dose (mg/kg)	Body weight, BW (g)	Liver weight, LW (g)	LW/BW (%)
Normal	—	207.9 ± 4.741	6.190 ± 0.3565	2.967 ± 0.1097
10% DMSO + PCM	—	217.5 ± 8.258	8.797 ± 0.7331^a	4.023 ± 0.2399^a
NAC + PCM	50	189.9 ± 2.697^a	8.232 ± 0.3992^a	4.326 ± 0.1522^a
MEMC + PCM	50	193.3 ± 9.105^b	8.009 ± 0.5417^a	4.136 ± 0.1568^a
	250	195.9 ± 1.893^ab	8.844 ± 0.1816^a	4.513 ± 0.0718^a
	500	176.7 ± 3.130^ab	6.340 ± 0.4192^b	3.583 ± 0.2096^b

Values are expressed as means ± SEM of six replicates.
^aSignificantly different as compared to normal control group, 𝑃<0.05. ^bSignificantly different as compared to negative control group, 𝑃<0.05.