Research Article

Human Endogenous Retrovirus W Activity in Cartilage of Osteoarthritis Patients

Table 3

Prevalence of dsRNA, syncytin-1, and HERV-like particles in samples from OA and non-/early OA patients.

Material/methodIF syncytinIF dsRNAIEM syncytinIEM dsRNATEM VLPTEM budding

Chondrocytes OA20/22* (S)**20/22 (S)7/7 (S)7/7 (S)6/75/7
Cartilage OA7/7 (S)7/7 (S)22/2416/24
Chondrocytes non-OA4/7 (3 W, 1 S)3/7 (2 W, 1 S)4/7 (3 W, 1 S)3/7 (2 W, 1 S)1/8
Cartilage non-OA 3/5 (2 W, 1 S) 3/5 (2 W, 1 S)
Collagenase-treated supernatants OA3/4

Number of positive samples/total number of samples.
**S: strong staining; W: weak staining; VLP: virus-like particles.