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BioMed Research International
Volume 2014, Article ID 703253, 13 pages
http://dx.doi.org/10.1155/2014/703253
Research Article

Cationic Polyene Phospholipids as DNA Carriers for Ocular Gene Therapy

1Center for Biomedicine and Structural Biology (CBME), Institute for Biotechnology and Bioengineering (IBB), University of Algarve, 8005-139 Faro, Portugal
2Doctoral Program in Biomedical Sciences, Department of Biomedical Sciences and Medicine, University of Algarve, 8005-139 Faro, Portugal
3ProRegeM Doctoral Program, Department of Biomedical Sciences and Medicine, University of Algarve, 8005-139 Faro, Portugal
4Department of Chemistry, Norwegian University of Science and Technology, 7491 Trondheim, Norway
5Premedical Unit, Weill Cornell Medical College in Qatar, P.O. Box 24144, Doha, Qatar
6Department of Biomedical Sciences and Medicine, University of Algarve, 8005-139 Faro, Portugal

Received 28 April 2014; Accepted 18 June 2014; Published 24 July 2014

Academic Editor: Taiyoun Rhim

Copyright © 2014 Susana Machado et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

S1: Transfection efficiency of novel cationic polyene lipids in another retinal cell line, D407. Comparison with Gene Juice, a commercial reagent, shows a similar trend.

S2: Flow cytometry scatter plots for cell transfection with the novel cationic polyene lipids.

  1. Supplementary Material