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BioMed Research International
Volume 2014, Article ID 703693, 4 pages
Research Article

Crosstalk among Taenia crassiceps (ORF Strain) Cysts Regulates Their Rates of Budding by Ways of Soluble and Contact Signals Exchanged between Them

Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, A.P. 70228, 04510 México, DF, Mexico

Received 20 February 2014; Accepted 9 May 2014; Published 28 May 2014

Academic Editor: Luis I. Terrazas

Copyright © 2014 Esquivel-Velázquez Marcela et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Herein we report that in vitro experiments with different initial parasite densities (1, 5, and 10 cysts per mL of culture medium) show that cysts at densities of 10 and 5 grow faster than those at 1, and that they release into the culture medium factors which increase the budding rates of the slower lower-density ones. Close contact among the incubated cysts also favors budding, thus suggesting the participation of surface sensors of parasite crowding. Thus, contact signals, together with the release of soluble growth factors, could endow cysts with the capacity to sense and regulate their numbers inside their habitat in relation to their population density.