Efficacy of a Hypotonic Treatment for Peritoneal Dissemination from Gastric Cancer Cells: An In Vivo Evaluation
Figure 1
Evaluation of the toxicity of the peritoneal injection of DW. (a) Two milliliters of NaCl buffer or DW was injected into the abdominal cavities of 4-week-old female BALB/c mice for 3 days. At a defined time point of 1 week after the start of the peritoneal injections, all mice were sacrificed, and intra-abdominal findings were investigated. . (b) No significant differences were observed in the representative macroscopic findings of abdominal organs, including the gastrointestinal tract, liver, and peritoneum, between the NaCl and DW groups. (c) No significant differences were observed in the representative histopathological findings of the small intestine, peritoneum, or liver between the NaCl and DW groups. Magnification: 100x. DW: distilled water.
