Antioxidant Defense Enzyme Genes and Asthma Susceptibility: Gender-Specific Effects and Heterogeneity in Gene-Gene Interactions between Pathogenetic Variants of the Disease
Table 4
A summary of best 2-, 3-, and 4-locus models of gene-gene interactions obtained by MDR analysis in allergic and nonallergic asthma (exhaustive search algorithm).
Number of loci
Best -locus (2-, 3-, and 4-locus) models of gene-gene interactions
best -locus model of gene-gene interactions evaluated through 1000 permutation tests.
**A statistically significant ( value 0.001) model of gene-gene interactions.