Serum Lipids, Apolipoproteins, and Mortality among Coronary Artery Disease Patients
Table 1
Baseline characteristics by outcomes among coronary artery disease patients.
Characteristic
All patients
Survivors
Nonsurvivors
for difference
(%)
1916
1769 (65.2)
147 (34.8)
Male (%)
65.2
64.3
75.5
0.006
Age at baseline (yrs)
63.7
63.0 (0.3)
72.4 (0.9)
<0.001
Body mass index (kg/m2)
23.9
23.9 (0.1)
23.6 (0.3)
0.22
Systolic blood pressure (mm Hg)
134
134 (0.6)
131 (2.0)
0.10
Diastolic blood pressure (mm Hg)
76
76 (0.3)
76 (1.1)
0.86
Fasting plasma glucose (mmol/L)
6.48
6.41 (0.06)
7.23 (0.23)
0.001
Total cholesterol (mg/dL)
181
181 (1.0)
181 (3.5)
0.97
LDL-C (mg/dL)
114
114 (0.9)
118 (3.2)
0.28
HDL-C (mg/dL)
42
42 (0.3)
40 (0.9)
0.04
Apolipoprotein A-I (mg/dL)
110
111 (0.6)
104 (2.2)
0.003
Apolipoprotein B (mg/dL)
78
78 (0.1)
80 (0.2)
0.39
LDL/HDL ratio
2.87
2.84 (0.03)
3.18 (0.09)
<0.001
Apolipoprotein B/A-I
0.95
0.96 (0.14)
0.85 (0.48)
0.82
Duration of CAD (yrs)
First diagnosed CAD ()
History of CAD ()
2.32 (0.75–7.47)
2.14 (0.68–7.00)
4.76 (1.03–10.0)
0.006
Married (%)
91.7
92.0
87.1
0.11
Years of education (%)
0.22
≤9
61.2
60.7
70.3
10–12
20.3
20.5
17.6
≥13
18.5
18.9
12.2
Smoking (%)
0.35
Never
60.3
60.0
64.1
Past
9.0
8.9
10.3
Current
30.7
31.1
25.5
Alcohol drinking (%)
0.52
Never
77.8
77.5
82.2
Past
7.2
7.3
5.6
Current
15.0
15.2
12.1
Leisure-time physical activity (%)
<0.001
None
34.6
33.5
55.1
<30 minutes/day
21.6
21.4
24.6
≥30 minutes/day
43.9
45.1
20.3
Type of CAD (%)
0.38
Acute coronary syndrome
57.9
58.2
54.4
Chronic CAD
42.1
41.8
45.6
Coronary artery stenosis degree of coronary angiography
0.003
Not conduct
34.6
33.8
44.0
<50%
13.2
13.8
5.7
50–74.9%
7.5
7.8
3.5
≥75%
44.7
44.6
46.8
GFR (mL/min/1.73 m2), (%)
<0.001
≥90
28.5
29.6
14.7
60–89
48.1
48.5
44.1
30–59
20.8
19.9
31.5
15–29
1.9
1.5
6.3
<15
0.7
0.5
3.5
History of diseases (%)
Hypertension
57.2
56.7
63.0
0.14
Diabetes
24.9
24.1
34.7
0.004
Dyslipidemia
28.9
29.5
21.1
0.03
Heart failure
42.4
41.3
55.8
0.001
Use of medication before admission (%)
Antihypertensive drugs
48.9
48.4
54.9
0.14
ACE inhibitors
14.9
14.8
16.7
0.54
Angiotensin II antagonists
20.2
19.9
23.6
0.29
Calcium antagonists
23.8
23.8
23.6
0.97
-blockers
27.8
28.2
22.9
0.17
Diuretics
8.6
7.8
17.4
<0.001
Antidiabetic drugs
16.5
16.0
22.9
0.03
Lipid-lowering drugs
12.0
12.5
6.9
0.05
Antiplatelet drugs
19.4
18.7
27.8
0.008
Treatment of CAD (%)
Coronary artery bypass graft
2.1
2.1
2.7
0.61
Percutaneous coronary intervention
50.6
50.5
51.0
0.91
Data are mean (SE) or percentage, except duration of CAD is shown median (lower-upper quartiles); all continuous variables are adjusted for age and gender.
