Potent Anti-Inflammatory Activity of Carbohydrate Polymer with Oxide of Zinc
Effects of Pebisut on inflammatory cytokine production induced by LPS. Peripheral blood mononuclear cells were purified and incubated in the presence of Pebisut (1 : 100 or 1 : 500) with or without LPS (100 ng/mL) stimulation during 18 hrs. After incubation, supernatants were collected to determinate cytokine concentration by CBA. (a) IL-6, (b) TNF, (c) IL-1β, (d) IL-8, and (e) nitrite. The data are expressed as the mean ± SEM and were analyzed with one-way ANOVA followed by Bonferroni’s comparison test (, , and ). Data are representative of three independent experiments.