Potent Anti-Inflammatory Activity of Carbohydrate Polymer with Oxide of Zinc
Chemotaxis induced by CCL2, CCL5, and CXCL12 is reduced by Pebisut in PBMCs. Chemotaxis assays with PBMCs were performed using membranes of 5 μm pore, 2 × 105 cells per well were preincubated with Pebisut (1 : 100 or 1 : 500), and 100 ng/mL chemokines were added. (a) CCL2, (b) CCL5, and (c) CXCL12. The data are expressed as the mean ± SEM and were analyzed with one-way ANOVA followed by Bonferroni’s comparison test (, , and ). Data are representative of three independent experiments.