Research Article
A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis
Table 10
GSEA using transcriptome data of PBMCs from human patients with other inflammatory or pathological conditions.
| Group comparison1 | THP1r2Mtb-induced | TMtb-iNet | TMtb-iEx | NES2 | FDR3 | Correlation3 | NES2 | FDR3 | Correlation3 | NES2 | FDR3 | Correlation3 |
| Type I diabetes versus HC | −1.34 | 0.112 | Null | −1.21 | 0.329 | Null | −1.13 | 0.336 | Null | Staph versus HC | −1.09 | 0.305 | Null | −1.29 | 0.334 | Null | 1.00 | 0.441 | Null | Liver-transplant versus HC | −0.79 | 0.892 | Null | −0.92 | 1.000 | Null | 0.90 | 0.647 | Null | E. coli versus HC | −0.91 | 0.646 | Null | −1.02 | 1.000 | Null | 1.20 | 0.156 | Null | Melanoma versus HC | −0.91 | 0.641 | Null | −0.92 | 1.000 | Null | 0.92 | 0.622 | Null | SLE versus HC | −1.14 | 0.396 | Null | −1.22 | 0.540 | Null | −1.04 | 0.490 | Null | JIA versus HC | −0.74 | 1.000 | Null | −0.76 | 1.000 | Null | −0.73 | 0.908 | Null |
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1Staph: Staphylococcus aureus infection; liver-transplant: liver-transplant undergoing immunosuppressive therapy; melanoma: metastatic melanoma; SLE: systemic lupus erythematosus; JIA: systemic juvenile idiopathic arthritis.
2,3The same as Table 1.
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