Research Article
A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis
Table 2
GSEA using transcriptome data of separated cell populations from human PTB patients.
| | Group comparison1 | THP1r2Mtb-induced | TMtb-iNet | TMtb-iEx | | NES2 | FDR3 | Correlation3 | NES2 | FDR3 | Correlation3 | NES2 | FDR3 | Correlation3 |
| | Neut_PTB versus Neut_HC | 3.27 | 0.000 | Positive | 3.08 | 0.000 | Positive | 2.92 | 0.000 | Positive | | Mono_PTB versus Mono_HC | 2.98 | 0.000 | Positive | 2.93 | 0.000 | Positive | 2.67 | 0.000 | Positive | | CD4_PTB versus CD4_HC | 1.86 | 0.000 | Positive | 2.36 | 0.000 | Positive | 0.99 | 0.484 | Null | | CD8_PTB versus CD8_HC | 1.70 | 0.000 | Positive | 2.23 | 0.000 | Positive | 1.07 | 0.238 | Null |
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1Neut: purified neutrophils; Mono: purified monocytes; CD4: purified CD4+ T cells; CD8: purified CD8+ T cells [2].
2,3The same as Table 1.
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