A Derived Network-Based Interferon-Related Signature of Human Macrophages Responding to Mycobacterium tuberculosis

Table 4

GSEA using another transcriptome data of whole blood from human PTB patients undergoing clinical therapy.

Group comparison^1	THP1r2Mtb-induced			TMtb-iNet			TMtb-iEx
	NES^2	FDR^3	Correlation^3	NES^2	FDR^3	Correlation^3	NES^2	FDR^3	Correlation^3
PTB_wk1 versus PTB_wk0	−1.96	0.000	Negative	−1.82	0.000	Negative	−1.87	0.000	Negative
PTB_wk2 versus PTB_wk0	−2.04	0.000	Negative	−2.00	0.000	Negative	−1.80	0.000	Negative
PTB_wk4 versus PTB_wk0	−2.54	0.000	Negative	−2.37	0.000	Negative	−2.31	0.000	Negative
PTB_wk26 versus PTB_wk0	−2.71	0.000	Negative	−2.68	0.000	Negative	−2.38	0.000	Negative

¹PTB_wk0: PTB patients before drug treatment; PTB_wk1: 1 week after initiation of drug treatment; PTB_wk2: 2 weeks after initiation of drug treatment; PTB_wk4: 4 weeks after initiation of drug treatment; PTB_wk26: 26 weeks after initiation of drug treatment [20].
^2,3The same as Table 1.