Review Article
Efficacy of Alendronate for Preventing Collapse of Femoral Head in Adult Patients with Nontraumatic Osteonecrosis
Table 2
Methodological quality of included randomized controlled trials.
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The trials which randomization schedules were explicitly described could get an “Yes”. bThe trials which placebo was adequately decribed how to blind both patients and investigators were considered as “Double Blinded”. cIn Hsu’s study, they compared alendronate + extracorporeal shock wave treatment + hyperbaric oxygen therapy versus extracorporeal shock wave treatment alone. dThe level of evidence was rated on basis of Oxford Centre for Evidence-based Medicine-Levels of Evidence (March 2009) [36]. |