Correlation of Altered Expression of the Autophagy Marker LC3B with Poor Prognosis in Astrocytoma

Figure 4

Assessment of the relationship between LC3B protein expression and overall survival of astrocytoma patients using Kaplan-Meier method with log-rank test. High intensity of LC3B immunohistochemical staining was shown to predict poor prognosis. Similar survival curve was also found with negative or weak LC3B protein expression. By contrast, low and moderate levels of LC3B expression had a significant increase in survival when compared with those of weak or high LC3B levels.