Correlation of Altered Expression of the Autophagy Marker LC3B with Poor Prognosis in Astrocytoma

Table 1

Correlation between Beclin-1 and LC3B protein expression with clinicopathological parameters. 𝑃 values were determined by Chi-squares analysis. KPS: Karnofsky performance status scale.

Score	LC3B					Beclin-1
	0	1	2	3	𝑃	0	1	2	3	𝑃
Age					0.312					0.244
>65	16	19	14	15		9	17	18	20
<65	12	12	17	1		7	12	13	10
Gender					0.221					0.453
M	15	17	18	6		4	14	19	19
F	13	14	13	10		12	15	12	11
Tumor grade					0.563					0.312
I	2	5	3	0		0	2	4	4
II	4	8	2	2		1	4	5	6
III	5	4	6	2		4	5	4	4
IV	17	14	20	12		11	18	18	16
Radiation/chemotherapy					0.021*					0.071
Yes	8	10	24	15		8	18	19	21
No	20	21	7	1		8	11	12	9
KPS					0.452					0.549
>70	10	15	17	6		10	15	8	15
<70	18	16	14	10		6	14	23	15