50-year-old male with prostate cancer. (a) Axial T2WI showing low signal within the rightward aspect of the peripheral zone (∗). Note the normal-appearing contralateral peripheral zone (PZ) comprised of glandular elements. Also, the right rectoprostatic angle appears slightly ill-defined, although no definite bulge is seen. 50-year-old male with prostate cancer. (b) Axial T1WI showing an enlarged right external iliac chain lymph node, a regional lymph node according to the TNM staging system. This would comprise N1 disease, which would fall under Stage IV category.