Research Article

C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies

Figure 4

(a) Predominantly focal paranuclear- (Golgi-like) c-Kit protein (PFP-c-Kit) expression. Immunohistochemistry is performed with primary anti-c-KitR antibody. Single arrows indicate focal brown paranuclear cytoplasmic immunostained c-KitR. Double arrows indicate a vessel. Note as an internal positive control the red blood cells in the lumen of the vessel. ×400 magnification. (b) Particular of (a) at even more magnification. Immunohistochemistry is performed with primary anti-c-KitR antibody. Single arrows indicate brown paranuclear cytoplasmic (Golgi-like) immunostained c-KitR. Double arrows indicate microvessels. Note as an internal positive control the red blood cells in the lumen of microvessels. ×1000 in oil magnification.
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(a)
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(b)