C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies

Table 1

All tissue indexes analysed means ± standard deviations as a function of tumour malignancy grade and statistical significance of their changes between G1 versus G2, G1 versus G3, and G2 versus G3 CMCT groups by Student’s 𝑡-test.

CMCTs; (number of cases)	MVD; 400x; (0.19 mm^2)	MCGD; 400x; (0.19 mm^2)	MCDD; 400x; (0.19 mm^2)	PM-c-KitR expression; (0.19 mm^2)	PDC-c-KitR expression; (0.19 mm^2)	PFP-c-KitR expression; (0.19 mm^2)
G1 (36)	7±4	91±29	21±10	109±35	9±4	8±5
G2 (29)	9±5	84±33	24±11	99±24	11±4	10±6
G3 (32)	27±9	39±17	107±42	7±3	115±31	96±34
𝑡-test	G1 versus G2	G1 versus G2	G1 versus G2	G1 versus G2	G1 versus G2	G1 versus G2
𝑃 value	n.s.	n.s.	n.s.	n.s.	n.s.	n.s.
𝑡-test	G1 versus G3	G1 versus G3	G1 versus G3	G1 versus G3	G1 versus G3	G1 versus G3
𝑃 value	0.001	0.004	0.001	0.000	0.001	0.000
𝑡-test	G2 versus G3	G2 versus G3	G2 versus G3	G2 versus G3	G2 versus G3	G2 versus G3
𝑃 value	0.002	0.004	0.002	0.000	0.001	0.001