Baicalein Induces Apoptosis and Autophagy via Endoplasmic Reticulum Stress in Hepatocellular Carcinoma Cells
Figure 1
Baicalein inhibits proliferation of HCC cells. (a) Structures of the flavonoids used: baicalein, baicalin, wogonin, and wogonoside. (b) Human HCC cell lines Bel-7402 and SMMC-7721 were treated with 0, 25, 50, 100, and 200 μM of baicalein for 24 h (upper panel) or 48 h (down panel). Relative cell viability was determined by CCK-8 assay. (c) Bel-7402 and SMMC-7721 cells were treated with 0, 25, 50, 100, and 200 μM of baicalin for 24 h (upper panel) or 48 h (down panel). Relative cell viability was determined by CCK-8 assay. Data were expressed as mean ± SD. *, compared with control group.
