Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 735891, 8 pages
http://dx.doi.org/10.1155/2014/735891
Research Article

The Use of Hibiscus esculentus (Okra) Gum in Sustaining the Release of Propranolol Hydrochloride in a Solid Oral Dosage Form

Department of Pharmacy, Medical Faculty, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 21 October 2013; Revised 12 December 2013; Accepted 30 December 2013; Published 11 February 2014

Academic Editor: Gail B. Mahady

Copyright © 2014 Nurul Dhania Zaharuddin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Mishra, J. H. Clark, and S. Pal, “Modification of Okra mucilage with acrylamide: synthesis, characterization and swelling behavior,” Carbohydrate Polymers, vol. 72, no. 4, pp. 608–615, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. L. G. Bakre and K. T. Jaiyeoba, “Evaluation of a new tablet disintegrant from dried pods of Abelmuscus esculentus L (Okra),” Asian Journal of Pharmaceutical and Clinical Research, vol. 2, no. 3, pp. 83–91, 2009. View at Google Scholar · View at Scopus
  3. E. I. Okoye, A. O. Onyekweli, and O. O. Kunle, “Okra gum—an economic choice for the amelioration of capping and lamination in tablets,” Annals of Biological Research, vol. 2, no. 2, pp. 30–42, 2011. View at Google Scholar
  4. R. Malviya, “Extraction characterization and evaluation of selected mucilage as pharmaceutical excipient,” Polimery w Medycynie, vol. 41, no. 3, pp. 39–44, 2011. View at Google Scholar · View at Scopus
  5. M. S. Alamri, A. Mohamed, S. Hussain, and J. Xu, “Effect of Okra extract on properties of wheat, corn and rice starches,” Journal of Food, Agriculture & Environment, vol. 10, no. 1, pp. 217–222, 2012. View at Google Scholar · View at Scopus
  6. M. Venkata Srikanth, N. Sreenivasa Rao, S. Ambedkar Sunil, B. Janaki Ram, and V. R. Murthy Kolapalli, “Statistical design and evaluation of a propranolol HCl gastric floating tablet,” Acta Pharmaceutica Sinica B, vol. 2, no. 1, pp. 60–69, 2012. View at Google Scholar
  7. N. Tavakoli, R. Teimouri, and H. Hamishehkar, “Characterization and evaluation of Okra gum as a tablet binder,” Jundushapur Journal of Natural Pharmaceutical Products, vol. 3, no. 1, pp. 33–38, 2007. View at Google Scholar
  8. V. K. Ravindran, S. Vasa, S. Subadhra, D. Banji, O. Banji, and Y. M. Rao, “Comparative study of mucoadhesive polymers carbopol 974p and sodium carboxymethyl cellulose for single unit dosage of imatinib mesylate,” Malaysian Journal of Pharmaceutical Sciences, vol. 10, no. 1, pp. 61–77, 2012. View at Google Scholar
  9. E. I. Nep and B. R. Conway, “Characterization of grewia gum, a potential pharmaceutical excipient,” Journal of Excipients and Food Chemicals, vol. 1, no. 1, pp. 30–40, 2010. View at Google Scholar · View at Scopus
  10. V. Morillon, F. Debeaufort, M. Capelle, G. Blond, and A. Voilley, “Influence of the physical state of water on the barrier properties of hydrophilic and hydrophobic films,” Journal of Agricultural and Food Chemistry, vol. 48, no. 1, pp. 11–16, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. V. D. Kalu, M. A. Odeniyi, and K. T. Jaiyeoba, “Matrix properties of a new plant gum in controlled drug delivery,” Archives of Pharmacal Research, vol. 30, no. 7, pp. 884–889, 2007. View at Google Scholar · View at Scopus
  12. N. R. Jadhav, V. L. Gaikwad, K. J. Nair, and H. M. Kadam, “Glass transition temperature: basics and application in pharmaceutical sector,” Asian Journal of Pharmaceutics, vol. 3, no. 2, pp. 82–89, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. K. K. Adom, V. P. Dzogbefia, W. O. Ellis, and B. K. Simpson, “Solar drying of Okra—effects of selected package materials on storage stability,” Food Research International, vol. 29, no. 7, pp. 589–593, 1996. View at Publisher · View at Google Scholar · View at Scopus
  14. I. Mukherjee and M. Rosolen, “Thermal transitions of gelatin evaluated using DSC sample pans of various seal integrities,” Journal of Thermal Analysis and Calorimetry, vol. 114, no. 3, pp. 1161–1166, 2013. View at Google Scholar
  15. N. Bolourchian and S. Dadashzadeh, “pH-independent release of propranolol hydrochloride from HPMC-based matrices using organic acids,” Daru, vol. 16, no. 3, pp. 136–142, 2008. View at Google Scholar · View at Scopus
  16. N. P. Chodavarapu, R. B. Yendluri, H. Suryadevara, P. Reddy, and P. Chhatoi, “Formulation and evaluation of Abelmoschus esculentus mucilage based metformin hydrochloride floating matrix tablets,” International Journal of Pharmacy and Technology, vol. 3, no. 2, pp. 2725–2745, 2011. View at Google Scholar · View at Scopus
  17. S. Dash, P. N. Murthy, L. Nath, and P. Chowdhury, “Kinetic modeling on drug release from controlled drug delivery systems,” Acta Poloniae Pharmaceutica, vol. 67, no. 3, pp. 217–223, 2010. View at Google Scholar · View at Scopus