Research Article
Blood Monocyte Subsets and Selected Cardiovascular Risk Markers in Rheumatoid Arthritis of Short Duration in relation to Disease Activity
Table 1
Clinical characteristics and cardiovascular (CV) risk factors of RA patients and control subjects.
| | | RA patients ( = 27) | Control group ( = 22) | value | | | Mean (SD) | Mean (SD) |
| | Clinical characteristics | | | | | Age, years | 41.40 (9.65) | 38.13 (10.84) | 0.270 | | Female gender, (%) | 21 (77.78%) | 17 (77.27%) | 1.000 | | Smoking habit, number (%) | 12 (44.44%) | 4 (18.18%) | 0.069 | | RF positivity, (%) | 25 (86%) | — | NA | | aCCP positivity, (%) | 24 (92.30%) | — | NA | | Disease duration, months (median) |
12 [4; 24] | — | NA | | DAS28 | 4.42 (1.50) | — | NA | | Steroids, number (%) | 10 (37%) | — | NA | | NSAIDs, number (%) |
19 (70.37%) | — | NA | | Without NSAIDs or steroids, number (%) | 4 (14.8%) | — | NA | | Antihypertensives, number (%) |
2 (7.41%) | 0 | 0.490 | | hsCRP, mg/L | 15.92 (25.38) | 1.03 (0.89) | <0.001 | | Traditional CV risk factors | | | | | Systolic blood pressure, mmHg | 121.77 (18.11) | 113.86 (10.99) | 0.066 | | Diastolic blood pressure, mmHg | 80.03 (7.95) | 75.27 (6.60) | 0.041 | | Mean arterial pressure, mmHg | 93.95 (10.50) | 88.13 (7.18) | 0.032 | | Body mass index, kg/m2 | 23.36 (4.09) | 23.34 (2.72) | 0.876 | | Glucose, mmol/L | 4.64 (0.40) | 5.02 (0.63) | 0.015 | | TC, mmol/L | 5.03 (1.24) | 5.20 (0.70) | 0.552 | | LDL-C, mmol/L | 3.06 (0.96) | 3.05 (0.74) | 0.959 | | HDL-C, mmol/L | 1.57 (0.41) | 1.73 (0.45) | 0.316 | | Triglycerides, mmol/L | 0.94 (0.47) | 0.93 (0.37) | 0.795 | | IMT (mm) | 0.43 (0.04) | 0.48 (0.11) | 0.114 |
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Data are shown as means (SD) or medians [interquartile range, IRQ] or percentages (%). NA: not applicable; RA: rheumatoid arthritis; RF: rheumatoid factor; aCCP: anticyclic citrullinated peptide antibodies; DAS28: disease activity score in 28 joints; NSAIDs: nonsteroidal anti-inflammatory drugs; hsCRP: high-sensitivity C-reactive protein; TC: total cholesterol; LDL-C: low-density lipoproteins-cholesterol; HDL-C: high-density lipoproteins-cholesterol; IMT: intima media thickness.
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