Review Article

Chondrogenic Differentiation of Human Adipose-Derived Stem Cells: A New Path in Articular Cartilage Defect Management?

Table 2

Expressed chondrogenic genes that are detectable at the different stages of differentiation over time (0 to 21 days) [12].

Chondrogenic differentiationExpressed genes

Stage ICollagen I, collagen VI
SOX 4
BMP 2

Stage IICOMP
HAPLN1
Collagen XI
SOX 9

Stage IIIMatrilin 3
Indian hedgehog
Homeobox 7
Chondroadherin
WNT 11

Stage IVAggrecan
Alkaline phosphatase
Collagen II, collagen IX, and collagen X
Fibromodulin
Osteocalcin
PTHrP