SNP rs8099917 in Gene IL28B Might Be Associated with Risk of Chronic Infection by HCV but Not with Response to Treatment

Table 1

Genotypic and allelic frequencies of SNP rs12979860 and rs8099917 in gene IL28B in individuals with chronic hepatitis C virus infection and the control group, Belém, 2012.

SNPs	Patients 𝑛 (%)	Controls 𝑛 (%)	𝑃^a	OR (CI 95%)	𝑃^b
rs12979860
Genotypes
CC	18 (24.0)	34 (36.7)	0.1865	0.5944 (0.3031–1.1659)	0.1761
CT	37 (49.3)	47 (48.0)		1.0566 (0.5789–1.9283)	0.9795
TT	20 (26.7)	17 (17.3)		1.7326 (0.8336–3.6013)	0.1955
Alleles
C	73 (48.7)	115 (58.7)	0.0813	0.6678 (0.4352–1.0247)	0.0813
T	77 (51.3)	81 (41.3)
rs8099917
Genotypes
GG	11 (14.7)	07 (7.1)	0.0600	1.2344 (0.8219–6.0745)	0.1754
GT	33 (44.0)	34 (34.7)		1.4790 (0.7979–2.7416)	0.2767
TT	31 (41.3)	57 (58.2)		0.5068 (0.2753–0.9329)	0.0413
Alleles
G	55 (36.7)	48 (24.5)	0.0195	1.7851 (1.1212–2.8420)	0.0195
T	95 (63.3)	148 (75.5)

aChi-square; bodds ratio.