| miRNA | Genomic location | Cancer type | Target | Phenotype | References |
| miR-34s | 1p36 and 11q23 | Colon cancer, neuroblastoma, pancreatic cancer, CLL, NSCLC, OSCC, breast cancer, bladder cancer, kidney cancer, melanoma | CDK4, CDK6, cyclin E2, E2F3, MYC BCL-2 | Cell-cycle arrest apoptosis | [14–16, 18, 51, 53, 54] |
| miR-107 | 10q23 | Colon cancer, breast cancer | CDK6, P130 | Cell-cycle arrest | [55–57] |
| miR-145 | 5q23 | Colon cancer, breast cancer, MDS, prostate cancer | MYC, E2F3, cyclin D2, CDK4, CDK6 | Cell-cycle arrest | [58–61] |
| miR-192/215 | 1q41 and 11q13 | Colon cancer, lung cancer, multiple myeloma, renal cancer | CDC7, MAD2L1 | Cell-cycle arrest | [66–69] |
| miR-200c | 12p13 | Breast cancer, ovarian cancer | FAP-1 | Apoptosis | [71, 81] |
| let-7 | Multiple locations (11 copies) | Lung cancer, colon cancer, ovarian cancer, breast cancer, lymphoma | CDK6, CDC25A, cyclin D, CDC34, MYC, E2F1, E2F3 | Cell-cycle arrest | [61, 83–90] |
| miR-15a/16-1 | 13q14 | B-CLL, pituitary adenomas, gastric cancer, NSCLC, prostate cancer, ovarian cancer, pancreatic cancer | CDK1, CDK2, CDK6, cyclin D1, D3, E1 BCL-2 | Cell-cycle arrest apoptosis | [98–112] |
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