Association of a miRNA-137 Polymorphism with Schizophrenia in a Southern Chinese Han Population

Table 3

Analysis of clinical characteristics between patients with TT and GT + GG genotypes.

Variables	(TT/GT + GG)	Genotype		Statistic tests
		TT	GT + GG
Age (Mean ± SD, year)	550/61	36.35 ± 14.04	37.41 ± 13.06	= 1.095	0.274
Disease duration (Mean ± SD, year)	550/61	10.43 ± 10.11	10.49 ± 9.38	= 0.045	0.964
Age at onset (Mean ± SD, year)	550/61	24.58 ± 10.24	26.82 ± 10.93	= 1.611	0.108
Male	348/44	23.85 ± 9.01	25.05 ± 9.68	= 0.824	0.411
Female	195/17	26.76 ± 11.14	31.42 ± 12.86	= 1.630	0.105
Family history +: (%)	79/8	79 (90.80)	8 (9.20)	= 0.070	0.791
Family history −: (%)	471/53	471 (89.89)	53 (10.11)
PANSS (Mean ± SD)
Total score	533/60	80.16 ± 18.27	79.52 ± 19.30	0.258	0.796
P subscore	533/60	22.45 ± 7.26	21.88 ± 7.53	0.575	0.565
N subscore	533/60	18.33 ± 8.12	19.23 ± 6.95	0.831	0.406
G subscore	533/60	36.83 ± 8.92	36.38 ± 8.94	0.362	0.717
BACS (Mean ± SD)
Digit sequencing task	185/24	15.58 ± 9.56	19.71 ± 8.18	2.016	0.045*
Category instances	185/24	30.92 ± 12.67	31.79 ± 12.19	0.317	0.752
Controlled oral word association test	185/24	10.04 ± 6.07	10.04 ± 5.21	0.001	0.999
List learning	185/24	22.29 ± 12.61	21.33 ± 13.93	0.346	0.730
Token motor task	185/24	46.14 ± 11.83	46.29 ± 12.64	0.061	0.952
Tower of London	185/24	7.62 ± 6.85	7.50 ± 1.12	0.083	0.934
Symbol coding	185/24	21.12 ± 12.68	18.71 ± 12.31	0.881	0.379

< 0.05.
SD: standard deviation; PANSS: Positive and Negative Syndrome Scale; P: Positive scale; N: Negative scale; G: General Psychopathology scale; BACS: Brief Assessment of Cognition in Schizophrenia.