The Role of Chemoattractant Receptors in Shaping the Tumor Microenvironment

Figure 2

Chemoattractant GPCRs in tumor microenvironment. A tumor has been recognized as a complicated “organ.” Various types of tumor and host cells, including immune cells, fibroblasts, endothelial cells, and progenitor cells of the tumor stroma, contribute to the tumor development, growth, metastasis, immune escape, and neovascularization.