Alterations of the Myovesical Plexus of the Human Overactive Detrusor

Figure 1

Suburothelial interstitial cells in control bladder. Multiple suburothelial cells with bizarre morphology and multiple processes coexpress a punctate signal for N-cadherin (green) and a filamentous signal for vimentin (red). Nuclei stained with Dapi (blue). Two cells are closely associated with each other (arrow). Cells expressing vimentin but lacking expression of N-cadherin embody fibroblasts (asterisk). Magnification X630. Binocular epifluorescent microscopy.