Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions

Table 1

ECM molecules and fragments with proangiogenic and antiangiogenic activity.

Proangiogenic	Antiangiogenic
Intact molecules	Fragments
Collagen I
Collagen III	Arresten
Collagen IV	Canstatin
Collagen XV	Tumstatin
Collagen XVIII	Restin
Fibrillin	Endostatin
Fibulin-1	Anastellin
Fibrin/fibrinogen	Heparin binding fragments
Fibronectin	Endorepellin
Glypican-1	Endostatin
Laminin-1	Elastin derived peptides
Laminin 8	Transient molecules
Perlecan	Thrombospondin-1
Tenascin C	Thrombospondin-2
Tenascin X
Vitronectin
Decorin
Fragments
Fragment E (fibrin)