Metabolic Effects of Hypoxia in Colorectal Cancer by ¹³C NMR Isotopomer Analysis

Figure 3

[U-¹³C]lactate exported by colon cancer cell lines to the incubation media during the first 8 hours of incubation under normoxia and hypoxia and low and high glucose media: (a) WiDr; (b) LS1034; (c) C2BBe1. Significant differences are indicated by * corresponding to 𝑃<0.05 (comparison between normoxia and hypoxia conditions) and # corresponding to 𝑃<0.05 (comparison between high and low cell media glucose concentrations (5 and 25 mM)).

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