Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014 (2014), Article ID 765426, 6 pages
http://dx.doi.org/10.1155/2014/765426
Research Article

Development and Characterization of Liposomal Doxorubicin Hydrochloride with Palm Oil

1Department of Pharmacy, Faculty of Medicine, University of Malaya, 51200 Kuala Lumpur, Malaysia
2Faculty of Pharmacy, Cyberjaya University College of Medical Sciences, 63000 Cyberjaya, Selangor, Malaysia
3Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 141176, Iran

Received 17 December 2013; Revised 11 February 2014; Accepted 17 February 2014; Published 27 March 2014

Academic Editor: Paolo Colombo

Copyright © 2014 Bahareh Sabeti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. O. Tacar, P. Sriamornsak, and C. R. Dass, “Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems,” Journal of Pharmacy and Pharmacology, vol. 65, no. 2, pp. 157–170, 2013. View at Google Scholar
  2. A. A. Gabizon, O. Lyass, G. J. Berry, and M. Wildgust, “Cardiac safety of pegylated liposomal doxorubicin (Doxil/Caelyx) demonstrated by endomyocardial biopsy in patients with advanced malignancies,” Cancer Investigation, vol. 22, no. 5, pp. 663–669, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. A. A. Gabizon, “Selective tumor localization and improved therapeutic index of anthracyclines encapsulated in long-circulating liposomes,” Cancer Research, vol. 52, no. 4, pp. 891–896, 1992. View at Google Scholar · View at Scopus
  4. A. Gabizon, D. Goren, A. T. Horowitz, D. Tzemach, A. Lossos, and T. Siegal, “Long-circulating liposomes for drug delivery in cancer therapy: a review of biodistribution studies in tumor-bearing animals,” Advanced Drug Delivery Reviews, vol. 24, no. 2-3, pp. 337–344, 1997. View at Publisher · View at Google Scholar · View at Scopus
  5. V. P. Torchilin, “Recent advances with liposomes as pharmaceutical carriers,” Nature Reviews Drug Discovery, vol. 4, no. 2, pp. 145–160, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. D. O. Edem, “Palm oil: biochemical, physiological, nutritional, hematological, and toxicological aspects: a review,” Plant Foods for Human Nutrition, vol. 57, no. 3-4, pp. 319–341, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. C. E. Elson and A. A. Qureshi, “Coupling the cholesterol- and tumor-suppressive actions of palm oil to the impact of its minor constituents on 3-hydroxy-3-methylglutaryl coenzyme a reductase activity,” Prostaglandins Leukotrienes and Essential Fatty Acids, vol. 52, no. 2-3, pp. 205–208, 1995. View at Publisher · View at Google Scholar · View at Scopus
  8. J. P. Kamat and T. P. A. Devasagayam, “Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria,” Neuroscience Letters, vol. 195, no. 3, pp. 179–182, 1995. View at Publisher · View at Google Scholar · View at Scopus
  9. M. R. Mozafari, “Liposomes: an overview of manufacturing techniques,” Cellular and Molecular Biology Letters, vol. 10, no. 4, pp. 711–719, 2005. View at Google Scholar · View at Scopus
  10. M. Riaz, “Liposomes preparation methods,” Pakistan Journal of Pharmaceutical Sciences, vol. 19, no. 1, pp. 65–77, 1996. View at Google Scholar
  11. L. D. Mayer, L. C. L. Tai, M. B. Bally, G. N. Mitilenes, R. S. Ginsberg, and P. R. Cullis, “Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients,” Biochimica et Biophysica Acta, vol. 1025, no. 2, pp. 143–151, 1990. View at Publisher · View at Google Scholar · View at Scopus
  12. G. Gregoriadis, “Entrapment of drugs and other materials into liposomes,” in Liposome Technology, vol. 2, Informa HealthCare, 3rd edition, 2007. View at Google Scholar
  13. G. Niu, B. Cogburn, and J. Hughes, “Preparation and characterization of doxorubicin liposomes,” in Cancer Nanotechnology, pp. 211–219, Springer, 2010. View at Google Scholar
  14. M. Traïkia, D. E. Warschawski, M. Recouvreur, J. Cartaud, and P. F. Devaux, “Formation of unilamellar vesicles by repetitive freeze-thaw cycles: characterization by electron microscopy and 31P-nuclear magnetic resonance,” European Biophysics Journal, vol. 29, no. 3, pp. 184–195, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Mu and Z. Zhong, “Preparation and properties of poly(vinyl alcohol)-stabilized liposomes,” International Journal of Pharmaceutics, vol. 318, no. 1-2, pp. 55–61, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Almgren, K. Edwards, and G. Karlsson, “Cryo transmission electron microscopy of liposomes and related structures,” Colloids and Surfaces A, vol. 174, no. 1-2, pp. 3–21, 2000. View at Publisher · View at Google Scholar · View at Scopus
  17. P. N. Gupta, V. Mishra, A. Rawat et al., “Non-invasive vaccine delivery in transfersomes, niosomes and liposomes: a comparative study,” International Journal of Pharmaceutics, vol. 293, no. 1-2, pp. 73–82, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. N. Heldt, M. Gauger, J. Zhao, G. Slack, J. Pietryka, and Y. Li, “Characterization of a polymer-stabilized liposome system,” Reactive and Functional Polymers, vol. 48, no. 1, pp. 181–191, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Fogli, R. Danesi, F. Innocenti et al., “An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma,” Therapeutic Drug Monitoring, vol. 21, no. 3, pp. 367–375, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Pereira-Lachataignerais, R. Pons, P. Panizza, L. Courbin, J. Rouch, and O. López, “Study and formation of vesicle systems with low polydispersity index by ultrasound method,” Chemistry and Physics of Lipids, vol. 140, no. 1-2, pp. 88–97, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Mazuel, J. Grove, G. Gerin, and K. P. Keenan, “HPLC-MS/MS determination of a peptide conjugate prodrug of doxorubicin, and its active metabolites, leucine-doxorubicin and doxorubicin, in dog and rat plasma,” Journal of Pharmaceutical and Biomedical Analysis, vol. 33, no. 5, pp. 1093–1102, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Panwar, B. Pandey, P. C. Lakhera, and K. P. Singh, “Preparation, characterization, and in vitro release study of albendazole-encapsulated nanosize liposomes,” International Journal of Nanomedicine, vol. 5, no. 1, pp. 101–108, 2010. View at Google Scholar · View at Scopus
  23. P. Saarinen-Savolainen, T. Järvinen, H. Taipale, and A. Urtti, “Method for evaluating drug release from liposomes in sink conditions,” International Journal of Pharmaceutics, vol. 159, no. 1, pp. 27–33, 1997. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Sznitowska and M. Stokrocka, “Determination of diclofenac released from suppositories using UV spectrophotometry, spectra derivative spectrophotometry and HPLC,” Acta Poloniae Pharmaceutica, vol. 64, no. 5, pp. 401–405, 2007. View at Google Scholar · View at Scopus
  25. A. Iwasa, H. Akita, I. Khalil, K. Kogure, S. Futaki, and H. Harashima, “Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature,” Biochimica et Biophysica Acta, vol. 1758, no. 6, pp. 713–720, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Miglietta, R. Cavalli, C. Bocca, L. Gabriel, and M. Rosa Gasco, “Cellular uptake and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or paclitaxel,” International Journal of Pharmaceutics, vol. 210, no. 1-2, pp. 61–67, 2000. View at Publisher · View at Google Scholar · View at Scopus
  27. F.-Q. Hu, X.-L. Wu, Y.-Z. Du, J. You, and H. Yuan, “Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 69, no. 1, pp. 117–125, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Park and H. S. Yoo, “In vivo and in vitro anti-cancer activities and enhanced cellular uptakes of EGF fragment decorated doxorubicin nano-aggregates,” International Journal of Pharmaceutics, vol. 383, no. 1-2, pp. 178–185, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Yuan, J. Miao, Y.-Z. Du, J. You, F.-Q. Hu, and S. Zeng, “Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells,” International Journal of Pharmaceutics, vol. 348, no. 1-2, pp. 137–145, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. C. Nastruzzi, Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications, CRC Press, 2004.
  31. M. Cheng, X. Gao, Y. Wang et al., “Synthesis of glycyrrhetinic acid-modified chitosan 5-fluorouracil nanoparticles and its inhibition of liver cancer characteristics in vitro and in vivo,” Marine Drugs, vol. 11, no. 9, pp. 3517–3536, 2013. View at Publisher · View at Google Scholar
  32. R. G. Gilbert, M. Hess, A. D. Jenkins, R. G. Jones, P. Kratochvíl, and R. F. T. Stepto, “Dispersity in polymer science,” Pure and Applied Chemistry, vol. 81, no. 2, pp. 351–353, 2009. View at Publisher · View at Google Scholar · View at Scopus