Gender-Dependent Effect of GSTM1 Genotype on Childhood Asthma Associated with Prenatal Tobacco Smoke Exposure

Table 1

Allergic diseases in children with or without prenatal TSE at 6 years of age (6 y) and with different GSTM1 genotypes.

	Prenatal TSE	No prenatal TSE		OR	95% CI
6 y dermatitis	48/156	140/435	0.745	0.937	0.631–1.390
GSTM1 null	30/95	77/252	0.854	1.049	0.631–1.745
GSTM1 positive	18/61	63/183	0.480	0.797	0.425–1.496
6 y rhinitis	90/156	230/435	0.300	1.215	0.840–1.758
GSTM1 null	60/95	134/252	0.095	1.510	0.930–2.451
GSTM1 positive	30/61	96/183	0.657	0.877	0.491–1.566
6 y asthma	49/156	89/435	0.006	1.780	1.181–2.684
GSTM1 null	32/95	45/252	0.002	2.337	1.370–3.985
GSTM1 positive	17/61	44/183	0.550	1.221	0.634–2.348