A Functional Interplay between 5-Lipoxygenase and μ-Calpain Affects Survival and Cytokine Profile of Human Jurkat T Lymphocyte Exposed to Simulated Microgravity

Table 2

Time-dependent effect of simulated microgravity on 5-LOX activity in Jurkat cells.

Sample	LOX activity (% of 1g cells)^a
1g cells	100 ± 11
4-hour sim-g cells	213 ±
24-hour sim-g cells	249 ±
48-hour sim-g cells	235 ±

100% of 5-LOX activity = 89 ± 7 pg of LTB₄/1 10⁶ cells. denotes < 0.01 versus 1g cells.