BMP-4 Genetic Variants and Protein Expression Are Associated with Platinum-Based Chemotherapy Response and Prognosis in NSCLC

Table 4

The association between the BMP-4 genotype and the BMP-4 protein expression in tumor samples was analyzed.

Genotype	High BMP-4 expression; 𝑁=36	%	Low BMP-4 expression; 𝑁=57	%	𝑃^†
−5826G > A
GG	11	31%	19	33%	0.961
GA	15	42%	23	40%
AA	10	28%	15	26%
6007C > T
TT	17	47%	13	23%	0.025
CT	13	36%	21	37%
CC	6	17%	23	40%

†Adjusted with age, sex, smoke status, histology, stage, and chemotherapy agents.