EXIA2: Web Server of Accurate and Rapid Protein Catalytic Residue Prediction
Figure 6
Structures around the catalytic residues of two example enzymes colored by residue structure flexibility and sequence conservation. The structures around the catalytic residues of Human ferrochelatase (PDB: 1HRK) and Oligo-1,6-glucosidase (PDB: 1UOK). The rainbow coloring in (a) and (c) is from blue (low structure rigidity or high structure flexibility) to red (high structure rigidity or low structure flexibility). (b) and (d) are colored from blue (low sequence conservation) to red (high sequence conservation). Structure flexibility and sequence conservation are based on the WCN model and PSI-Blast PSSM as described in Section 3. The black arrows in the figure indicate the direction of side chain vector for the catalytic residues.
